Phosphopyruvate hydratase complex
Web14-3-2-protein, 2-phospho-D-glycerate hydro-lyase (phosphoenolpyruvate-forming), 2-phospho-D-glycerate hydro-lyase activity, 2-phospho-D-glycerate-hydrolase activity, 2 … WebJul 5, 2005 · Phosphopyruvate hydratase; catalyzes the hydrolysis of 2-phosphoglycerate to phosphoenolpyruvate during glycolysis and the reverse reaction during gluconeogenesis; localized to mitochondria and vacuoles View computational annotations Molecular Function Manually Curated enables melatonin binding ( IDA )
Phosphopyruvate hydratase complex
Did you know?
WebFunction Multifunctional enzyme that acts as an enolase involved in the metabolism and as a positive regulator of cold-responsive gene transcription ( PubMed: 12032082 ). Binds to the cis-element the gene promoter of STZ/ZAT10, a zinc finger transcriptional repressor ( PubMed: 12032082 ). Catalytic activity
WebAconitate hydratase 1; Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis- aconitate. Could catalyze the hydration of 2-methyl-cis ... WebMay 29, 2024 · It identifies long open reading frames (ORFs) within transcripts and scores them according to their sequence composition. Those ORFs that encode sequences with compositional properties (codon frequencies) consistent with coding transcripts are reported. Running TransDecoder is a two-step process.
WebIs identified as an autoantigen in Hashimoto encephalopathy (HE) a rare autoimmune disease associated with Hashimoto thyroiditis (HT). HT is a disorder in which destructive … WebEnolase, also known as phosphopyruvate hydratase, is a key glycolytic enzyme in the cytoplasm of prokaryotic and eukaryotic cells. It is a metalloenzyme that requires the …
Phosphopyruvate hydratase, usually known as enolase, is a metalloenzyme (EC 4.2.1.11) that catalyses the conversion of 2-phosphoglycerate (2-PG) to phosphoenolpyruvate (PEP), the ninth and penultimate step of glycolysis. The chemical reaction is: 2-phospho-D-glycerate See more In humans there are three subunits of enolase, α, β, and γ, each encoded by a separate gene that can combine to form five different isoenzymes: αα, αβ, αγ, ββ, and γγ. Three of these isoenzymes (all homodimers) are … See more Using isotopic probes, the overall mechanism for converting 2-PG to PEP is proposed to be an E1cB elimination reaction involving a carbanion intermediate. The following detailed mechanism is based on studies of crystal structure and See more Small-molecule inhibitors of enolase have been synthesized as chemical probes (substrate-analogues) of the catalytic mechanism of the enzyme and more recently, have been investigated as potential treatments for cancer and infectious diseases. … See more Enolase is a member of the large enolase superfamily. It has a molecular weight of 82,000-100,000 Daltons depending on the isoform. In human alpha enolase, the two subunits are See more In recent medical experiments, enolase concentrations have been sampled in an attempt to diagnose certain conditions and their severity. For example, higher concentrations of … See more • Holt A, Wold F (December 1961). "The isolation and characterization of rabbit muscle enolase". The Journal of Biological Chemistry. 236 (12): … See more • Enolase at the U.S. National Library of Medicine Medical Subject Headings (MeSH) See more
WebNov 16, 2024 · The strictly conserved αSer162 residue in the Co-type nitrile hydratase from Pseudonocardia thermophila JCM 3095 (PtNHase), which forms a hydrogen bond to the axial αCys108-S atom, was mutated into an Ala residue. The αSer162Ala yielded two different protein species: one was the apoform (αSerA) that exhibited no observable … cincinnatus town hallWebSummary Enables melatonin binding activity and phosphopyruvate hydratase activity. Involved in glycolytic process and regulation of vacuole fusion, non-autophagic. Located in cytoplasmic side of plasma membrane; fungal-type vacuole; and mitochondrion. Part of phosphopyruvate hydratase complex. cincinnatus town clerk hoursWebStructure. ENO3 is one of three enolase isoforms, the other two being ENO1 (ENO-α) and ENO2 (ENO-γ). Each isoform is a protein subunit that can form hetero-or homodimers of the following combinations: αα, αβ, αγ, ββ, and γγ.. Gene. The ENO3 gene spans 6 kb and contains 12 exons, though the first exon is an untranslated region and, thus, non-coding. . … cincinnatus town courtWeb神经元特异性烯醇化酶 （英語： neuron specific enolase ，缩写 NSE ），也称为 烯醇化酶2 （enolase 2， ENO2 ）、 γ-烯醇化酶 （Gamma-enolase）是 人类基因组 中编码的三种 烯醇化酶 （也称做“磷酸烯醇式丙酮酸水合酶”， phosphopyruvate hydratase）之一，是 小细胞肺癌 和 嗜铬细胞瘤 的 肿瘤标志物 。 参考文献 [ 编辑] ^ 1.0 1.1 1.2 GRCh38: Ensembl … cincinnatus storyWebLiterature; Reviews; News; Aging human genes; Digital aging atlas; Aging cell; Age induced pathology; homosapiens; Age induced physiological changes; Age induced psychological changes cincinnatus titleWebJan 23, 2007 · phosphoenolpyruvate CHEBI:58702 zoom Cofactor Protein has 1 cofactor binding site: Mg2+ ( UniProtKB Rhea CHEBI:18420 ) Note: Mg 2+ is required for catalysis and for stabilizing the dimer. Pathway Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5. Features Showing features for active site, binding … di-2 ethyl hexyl phthalate cas numberWebImagine registered nurses, mental and behavioral health specialists, health coaches, and other professionals, ready to match their expertise to your needs. Talk with a Team Blue … di 2-ethylhexyl phthalate “dehp”