Line-1 orf1p antibody
Nettet3. jan. 2024 · ORF1p, a nucleic acid chaperone that binds LINE-1 mRNA, was predominantly expressed in the cytoplasm, with minor localization in the nucleus. ORF2p, containing endonuclease and reverse transcriptase domains, exhibited punctate foci in the nucleus and also displayed co-localization with PCNA and γH2AX. Nettet1. jun. 2024 · The LINE1-ORF1p antibody prepared had a titer of >1:16 000 and could specifically recognize LINE1-ORF1p in cells and tumor tissue. WT_CLS1 cells transfected with pEGFP-N1-LINE1-ORF1 had significant increases in the mRNA and protein expression of LINE1-ORF1 and significantly enhanced cell proliferation ability and …
Line-1 orf1p antibody
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Nettet29. des. 2024 · These studies demonstrated expression and sub-cellular localization of LINE-1 proteins, ORF1p, with antibody 4H1, and ORF2p, with antibody chA1-L1. Results Here we conduct immunoprecipitation/mass spectrometry analysis using chA1-L1 antibody against ORF2p in LNCaP cells. Nettet27. jul. 2024 · The L1 element encodes two proteins, ORF1p and ORF2p. ORF1p is an RNA binding protein with nucleic acid chaperone activity, while ORF2p has endonuclease and reverse transcriptase activity (Alisch et al. 2006; Khazina et al. 2011; Martin et al. 2003; Martin and Bushman 2001 ).
Nettet27. jan. 2024 · This study generated new LINE-1 ORF1p peptide antibodies. References Zheng, L. et al. Incidence and mortality of ovarian cancer at the global, regional, and … NettetAnti-mouse LINE-1 ORF1p rabbit polyclonal antibodies. This fantastic reagent was developed and characterized by Sandy Martin in 1991. As the piRNA field took off in 2006, this polyclonal antibody has become very popular following our first description of Maelstrom knockout male mice.
NettetThis product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility. - Improved sensitivity … NettetImmunofluorescent analysis of 4% paraformaldehyde-fixed, 0.1% Triton X-100 permeabilized MCF7 (human breast adenocarcinoma cell line) cells labeling LINE-1 …
NettetLINE 1 ORF1p Rabbit pAb. Gene Name ... Nucleic acid-binding protein which is essential for retrotransposition of LINE-1 elements in the genome. ... Primary Antibody. Host Rabbit. Reactivity Human. Application WB,IHC-P. …
NettetThis product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free … danske it and support servicesNettetLINE1-ORF 1P serves as a nucleic acid-binding protein that is essential for retrotransposition of LINE-1 elements in the genome. It is also reported to function as a … dansk hanna clear iced beverageNettet31. des. 2024 · Johns Hopkins University has licensed these LINE-1 monoclonal ORF2p antibodies for commercialization to Abcam (Cambridge, UK). D.A., M.S.T., and K.H.B. will receive royalties from sales. K.H.B. and M.S.T. receive royalties from sales of a LINE-1 ORF1p monoclonal antibody licensed to EMD Millipore by Johns Hopkins University. danske bank schools cup final 2023NettetAnti-LINE-1 ORF1p, clone 4H1 ZooMAb ®, Cat. No. ZMS1066, is a recombinant Mouse monoclonal antibody that specifically targets LINE-1 ORF1p and is tested for use in … birthday poster with pictureNettetLINE-1 ORF1p is a component of apoptotic blebs and a substrate for GrB. Anti-ORF1p antibodies are enriched in SLE subjects but are not associated with dynamic markers of … birthday post for girlfriendNettet丁香通为您提供CRYGARabbitp商品详情介绍：价格：￥600 - 1800，货号：db4048，品牌：戴格，详见丁香通CRYGARabbitp商品详情页； dansk grand prairie hickory flooringNettet10. nov. 2024 · “Across most major carcinoma types in our initial study, the rates of finding overexpression in LINE-1 transposon were between 50 and 95 percent or higher.” A family of transposons known as long interspersed nuclear element 1 (LINE-1), including the open reading frame 1 protein (ORF1p), appear in many forms of cancer—possibly even … dansk google chrome download