Web10 de abr. de 2024 · Primary aldosteronism, eponymously known as Conn’s syndrome, has recently gained recognition as the most common cause of endocrine hypertension. Unilateral subtypes, such as aldosterone secreting adenomas, are managed surgically and are potentially curable. The background of refractory hypertension and hypokalaemia in … Web31 de ago. de 2024 · Although the explanation underlying why primary aldosteronism is so common in the normotensive population is still under investigation, a leading hypothesis is the accumulation of pathogenic somatic mutations over the lifespan that result in inappropriately high aldosterone synthase expression, visualized as aldosterone …
Diagnosis and treatment of primary aldosteronism - The Lancet …
Web1 de mar. de 2024 · Primary aldosteronism (PA) is the most common endocrine-related secondary hypertension [1,2], accounting for 5-15% of all hypertensive patients, and the rate is even higher in patients with... Web13 de mai. de 2024 · Primary aldosteronism (PA) is a potentially curable form of secondary hypertension caused by excessive renin-independent aldosterone secretion, leading to increased target organ damage and cardiovascular morbidity and mortality. The diagnosis of PA requires measuring renin and aldosterone to calculate the aldosterone-to … how to say my love in venda
Management of patients with resistant hypertension: current …
Web4 de abr. de 2024 · TBX3 is a transcription factor sharing a common DNA-binding domain, T-box, and expresses in the adrenal gland. 41 TBX3 acted as a tissue-specific member of β-catenin transcriptional complex. 42 HOTTIP is presumed to regulate the expression of HOXA genes, and its dysregulation has been implicated in various tumors. 43 HOX … WebHow common is primary aldosteronism? Is it the most frequent cause of curable hypertension? . Authors R D Gordon 1 , S A Klemm , M Stowasser , T J Tunny , W J Storie , J C Rutherford Affiliation 1 Endocrine-Hypertension Research Unit, Greenslopes Hospital, Brisbane, Australia. PMID: 8158400 No abstract available Publication types Web1 de mar. de 2024 · Europe PMC is an archive of life sciences journal literature. Please help EMBL-EBI keep the data flowing to the scientific community! Take part in our Impact … how to say my man in french