Hippocalcin-like 1

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August undefined, 2024

Webbhippocalcin-like protein 1, NVL-3, neural visinin-like Ca2+-binding protein type 3, neural visinin-like protein 3, visinin-like protein 3 GeneRIFs: Gene References Into Functions direct comparison of the localization and calcium-dependent translocation of visinin-like-proteins 1 and 3 in hippocampal neurons WebbHippocalcin-like 1 (HPCAL1) is a calcium sensor protein. However, the biological function of HPCAL1 is poorly understood in cancers, including HCC. Herein, HPCAL1 was …

Hippocalcin-Like 1 blunts liver lipid metabolism to suppress ...

WebbHippocalcin is predominantly expressed in mammalian hippocampus, and has been implicated in interactions with Neuronal Apotosis Inhibitory Protein (NAIP), phospholipase D (PLD)/Cdc42, and Mixed Lineage Kinase 2 (MLK2) [43–45]. These studies link hippocalcin to endocytosis, MAP kinase, and apoptosis pathways. Webb24 okt. 2024 · Results: In this study, we identified hippocalcin-like protein 1 (HPCAL1) as an important negative regulator of de novo lipid biosynthesis and mTOR signaling activation, limiting liver tumorigenesis and establishing a metabolic vulnerability of … show us the money meme

鉴定 HPCAL1 作为参与铁死亡的特异性自噬受体,Autophagy - X-MOL

WebbThe protein encoded by this gene is highly similar to human hippocalcin protein and hippocalcin like-1 protein. It also has similarity to rat neural visinin-like Ca2+-binding protein-type 1 and 2 proteins. This encoded protein may be involved in the calcium-dependent regulation of rhodopsin phosphorylation. Webb3 feb. 2024 · Hippocalcin-like 4 (Hpcal4) belongs to the superfamily of visinin-like calcium binding proteins (CaBPs) and contributes to the inactivation of Cav2.1 channels . By regulating the levels of intracellular calcium, CaBPs contribute to a wide variety of cellular processes, including the transmission of nociceptive messages. WebbHippocalcin-like 1 is a key regulator of LDHA activation that promotes the growth of non-small cell lung carcinoma. These studies elucidate the tumour-promoting activity of … show us the father scripture

Hippocalcin‐like 1 suppresses hepatocellular carcinoma

Hippocalcin-like protein 1 - Wikipedia

WebbHPCAL1 is a neuronal calcium sensor with three EF-hand domains that belongs to a member of the visinin-like proteins (VILIP) superfamily, which include visinin-like … WebbSummary Gene: Hpcal1 (hippocalcin-like 1) Rattus norvegicus Add Watcher Analyze General Array IDs Annotation Click to see Annotation Detail View Disease Annotations … show us the snow in portstewartWebb13 dec. 2015 · Hippocalcin-like 1 (HPCAL1), a neuronal calcium sensor, belongs to the visinin-like protein (VILIP) superfamily. The VILIP family comprises VILIP1, VILIP2, VILIP3 (gene name HPCAL1), hippocalcin, and neurocalcin-δ, which possess four EF-hand calcium-binding motifs and a consensus myristoylation site at the NH2 terminus. 18 , 19 … show us the thug shaker

"Webb24 okt. 2024 · Results: In this study, we identified hippocalcin-like protein 1 (HPCAL1) as an important negative regulator of de novo lipid biosynthesis and mTOR signaling … " - Hippocalcin-like 1

Hippocalcin-like 1

Webb31 jan. 2024 · Hippocalcin-like 1 (HPCAL1), a neuronal calcium sensor protein family member, has been reported to regulate cancer growth. As yet, however, the biological functions of HPCAL1 and its molecular mechanisms have not been investigated in non-small cell lung carcinoma (NSCLC). Methods WebbGrade IV astrocytoma, also known as glioblastoma or glioblastoma multiforme (GBM) is the most common and aggressive glioma with a very poor 5-year survival (less than 5%). …

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http://www.cnreagent.com/show1001180/product_94342.html Webb17 feb. 2024 · It is highly similar to human hippocalcin protein and nearly identical to the rat and mouse hippocalcin like-1 proteins. It may be involved in the calcium-dependent regulation of rhodopsin phosphorylation and may be of relevance for neuronal signalling in the central nervous system.

Webb3 feb. 2024 · Calcium binding proteins are expressed throughout the central and peripheral nervous system and disruption of their activity has major consequences in a wide array of cellular processes, including transmission of nociceptive signals that are processed at the level of the spinal cord. Webb15444 Ensembl ENSG00000121905 ENSMUSG00000028785 UniProt P84074 P84075 RefSeq (mRNA) NM_002143 NM_001130419 NM_010471 NM_001286081 NM_001286083 RefSeq (protein) NP_002134 NP_001123891 NP_001273010 NP_001273012 NP_034601 Location (UCSC) Chr 1: 32.89 – 32.9 Mb Chr 4: 129.01 – …

Webb5 apr. 2024 · 任佳欣，程彩霞，杨彦娥1山西医科大学第一临床医学院，太原 0300012山西医科 ... 研究发现，海马钙素样1（hippocalcin like 1，HPCAL1）是一种钙传感器蛋白，可保护p21免受DTL的泛素化和蛋白酶体降解，从而诱导肝癌细胞生长停滞，降低HPCAL1的表达可促进G1/S期 ... WebbHuman diseases caused by Hpcal1 mutations. The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER. Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes. Human diseases associated with …

WebbHPCAL1, hippocalcin like 1 Vertebrate Orthologs 3 Vertebrate Orthology Source. Alliance of Genome Resources. Human Ortholog HPCAL1, hippocalcin like 1. Synonyms BDR1, HLP2, VILIP-3 Links HGNC:5145. NCBI Gene ID: 3241. neXtProt AC: NX_P37235. UniProt: P37235. Chr ...

WebbHere, we use a quantitative proteomic approach to identify HPCAL1 (hippocalcin like 1) as a novel autophagy receptor for the selective degradation of CDH2 (cadherin 2) … show us the vinWebbHippocalcin-like protein 1 is a member of neuron-specific calcium-binding proteins family found in the retina and brain. It is highly similar to human hippocalcin protein and nearly identical to the rat and mouse hippocalcin like-1 proteins. It may be involved in the calcium-dependent regulation of rhodopsin phosphorylation and may be of ... show us the songhttp://www.cloud-clone.com/items/C533.html show us the way songWebbHippocalcin-like protein 1 is a protein that in humans is encoded by the HPCAL1 gene. The protein encoded by this gene is a member of the neuron-specific calcium-binding … show us videosWebbHippocalcin-Like 1 blunts liver lipid metabolism to suppress tumorigenesis via directly targeting RUVBL1-mTOR signaling Authors - Tao Chen. View Article. human: IHC: Signal Transduct Target Ther. Blockade of NMT1 enzymatic activity inhibits N-myristoylation of VILIP3 protein and suppresses liver cancer progression show us thy glory oh lord lyricsWebb10 apr. 2024 · Here, we use a quantitative proteomic approach to identify HPCAL1 (hippocalcin like 1) as a novel autophagy receptor for the selective degradation of CDH2 (cadherin 2) during ferroptosis. HPCAL1-dependent CDH2 depletion increases susceptibility to ferroptotic death by reducing membrane tension and favoring lipid … show us the wayWebb23 jan. 2007 · Hippocalcin-like protein 1 Alternative names Calcium-binding protein BDR-1 HLP2 Visinin-like protein 3 ( VILIP-3) Gene names Name HPCAL1 Synonyms BDR1 … show us time zones map