WebNov 2, 2024 · Macrophages from Csf2ra-/- mice were unable to bind and clear GM-CSF, did not exhibit GM-CSF signaling, and had functional defects in phagocytosis, cholesterol clearance, and surfactant clearance. WebMar 21, 2024 · CSF2RA (Colony Stimulating Factor 2 Receptor Subunit Alpha) is a Protein Coding gene. Diseases associated with CSF2RA include Surfactant Metabolism …
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WebDescription: Homo sapiens colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) (CSF2RA), transcript variant 8, mRNA. RefSeq Summary (NM_001161530): The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the … WebThe granulocyte-macrophage colony-stimulating factor receptor also known as CD116 ( C luster of D ifferentiation 116 ), is a receptor for granulocyte-macrophage colony …
WebFeb 4, 2024 · From macrophage biology to macrophage-based cellular immunotherapies. As far back as 1882, Ilya (Elie) Metchnikoff was the first to discover macrophages (MΦ) and their important role in host ... WebDescription: Homo sapiens colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) (CSF2RA), transcript variant 10, mRNA. RefSeq Summary (NM_001161532): The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the …
Webcsf2ra Granulocyte-macrophage colony-stimulating factor receptor subunit alpha; Low affinity receptor for granulocyte-macrophage colony- stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells; Belongs to the type I cytokine receptor family. WebView mouse Csf2ra Chr19:61212395-61216867 with: phenotypes, sequences, polymorphisms, proteins, references, function, expression. Home; ... Mice homozygous for a null allele exhibit pulmonary alveolar proteinosis due to defects in macrophage clearance and abnormal bronchoalveolar fluid containing amorphous debris, peribronciolar …
WebOriginal Article Long-Term Safety and Efficacy of Gene-Pulmonary Macrophage Transplantation Therapy of PAP in Csf2ra / Mice Paritha Arumugam, 1,2Takuji Suzuki, 6 Kenjiro Shima, 1,2Cormac McCarthy, Anthony Sallese, Matthew Wessendarp, 1,2Yan Ma, Johann Meyer,5 Diane Black,1,2 Claudia Chalk, Brenna Carey, Nico Lachmann, …
WebCSF2RA. Status. UniProtKB reviewed (Swiss-Prot) Organism. Homo sapiens (Human) Amino acids. 400. Protein existence. Evidence at protein level. ... Function. function. Low … design for wedding cardWebLow affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of … chuck carstensen re/maxWebCD116, CSF2R, GMR-alpha, CSF2RA, Granulocyte-macrophage colony-stimulating factor receptor subunit alpha, CSF2RY, GMCSFR-alpha, GM-CSF-R-alpha, CDw116. Purification. Protein A or G purified from cell culture supernatant. Endotoxin level. Please contact with the lab for this information. Expression system. XtenCHO. Accession. chuck carstensenWebHuman Gene CSF2RA (uc004cpp.2) Description: Homo sapiens colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) (CSF2RA), transcript variant 3, mRNA. RefSeq Summary (NM_172246): chuck carswell crossfitWebJul 28, 2016 · By separating the mutations, we established unique Csf2ra-/- mouse model that allows study the role of cell intrinsic GM-CSF receptor signaling in vivo without confounding variables introduced by defective IL-5 receptor and IL-3 receptor signaling in mice lacking the common β chain (Csf2rb). chuck cars movieWebApr 8, 2024 · Finally, Csf2ra retroviral gene transfer into Csf2ra-deficient fetal liver monocytes restored their potential to develop into bona fide alveolar macrophages in … chuck carterWebCsf2ra : colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) Csf2ra : granulocyte-macrophage colony stimulating receptor alpha : Nomenclature … design foundry hickory